地点：材料学院D楼312室

时间：2019.5.23星期四 下午1：45

报告人：侯仰龙教授 （北京大学工学院）

报告题目与内容

Fabrication and Multifunctional Applications of Magnetic Nanomaterials

Yanglong Hou

Beijing Key Laboratory for Magnetoelectric Materials and Devices (BKLMMD), Beijing Innovation Center for Engineering Science and Advanced Technology (BIC-ESAT), Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China

Magnetic nanomaterials (MNMs) have attracted significant interest in the past few decades due to their unique properties such as superparamagnetism, which results from the influence of thermal energy on a ferromagnetic nanoparticle. To understand the fundamental behavior of nanomagnetism and develop relevant potential applications, various preparation routes have been explored to produce MNMs with desired properties and structures, among which chemical synthesis, especially high-temperature organic-phase method, play an indispensable role in which the microstructures and physical/chemical properties of MNMs can be tuned by controlling the reaction conditions such as precursor, surfactant, or solvent amounts, reaction temperature or time, reaction atmosphere, etc. In this talk, we first introduce the fundamental of high-temperature organic-phase method, and present the progress on the synthesis of plenty of MNMs, including monocomponent nanostructures (like metals, metal alloys, metal oxides/carbides) and multicomponent nanostructures (heterostructures and exchange-coupled nanomagnets). Considering the latter type not only retain the functionalities from each single component, but also possess synergistic properties that emerge from interfacial coupling, with improved magnetic, optical or catalytic features, and therefore, we will discuss the potential applications of MNMs in biomedicine and catalysis. For an instance, Fe5C2, one kind of representative iron carbide, have shown infinite possibilities. It showed intrinsic catalytic properties during Fischer−Tropsch synthesis, no matter in efficiency and selectivity. On the other hand, through modification of affinity proteins (ZHER2:342), Fe5C2 NPs can selectively bind to HER2 overexpressing cancer cells. T2-weighted MRI and PAT signals are readily observed, and tumors are effectively ablated by PTT under NIR irradiation. To enhance cancer therapeutic efficiency, anticancer drug doxorubicin is loaded into bovine serum albumin coated Fe5C2 NPs, combining PTT with chemotherapy. Such nanoplatform can respond to NIR and acidic environments, and exhibit burst drug release. In summary, we overview the rational design, fabrications of magnetic nanomaterials, this kind of materials give great application potential in biomedicine and nanocatalysis.

Keywords: Magnetic nanostructures, Synthesis, Therapy, MRI, PTT

REFRENCES

[1] K. Zhu, J. Xu, Z. Yang, Y. Hou S. Gao, Acc. Chem. Res., 2018, 51(2018), 404–413.

[2] F. Liu, Y. Hou, S. Gao, Chem. Soc. Rev., 43(2014), 8098-8113.

[3] J. Yu, X. Chu, Y. Hou, Chem. Commun., 50(2014), 11614-11630

[4] R. Hao, R. Xing, Z. Xu, Y. Hou, S. Gao, S. Sun, Adv. Mater., 22(2010) 2729– 2742.

[5] C. Yang, J. Wu, Y. Hou, Chem. Commun., 47(2011), 5130-5141.

[6] Z. Xu, C. Shen, Y. Hou, H. Gao, S. Sun. Chem. Mater., 21(2009), 1778−1780.

[7] C. Yang, H. Zhao, Y. Hou, D. Ma, J. Am. Chem. Soc., 134 (2012),15814−15821.

[8] J. Yu, C. Yang, J. Li, Y. Ding, L. Zhang, M.Z. Yousaf, J. Lin, R. Pang, L. Wei, L. Xu, Adv. Mater., 26 (2014), 4114−4120.

[9] J. Yu, Y. Ju, L. Zhao, X. Chu, W. Yang, Y, Tian, F. Sheng, J. Lin, F. Liu, Y. Dong and Y. Hou, ACS Nano, 10(2016), 159−169.

[10] Y. Ju, H. Zhang, J. Yu, S. Tong, N. Tian, Z. Wang, X. Wang, X. Su, X. Chu, J. Lin, Y. Ding, G. Li, F. Sheng, Y. Hou, ACS Nano, 11(2017), 9239−9248.

[11] Z. Wang, Y. Ju, S. Tong, H. Zhang, J. Lin, B. Wang , Y. Hou, Nano Horizon, 3(2018), 624−631.

报告人简介：

侯仰龙，教育部长江学者特聘教授，国家杰出青年科学基金获得者，皇家化学会会士（FRSC），万人计划科技创新领军人才，国家重点研发计划纳米科技专项首席科学家，磁电功能材料与器件北京市重点实验室主任，北京大学教授、博士生导师。主要从事多功能磁性材料、新能源材料的控制合成及其在纳米生物医学与能源领域的应用探索研究。发展了单分散磁性纳米材料的通用制备方法，探索了磁性纳米颗粒在肿瘤等重大疾病的诊断与治疗的应用；设计制备了若干纳米结构杂化材料用于高性能的锂电池电极等。迄今发表学术论文160余篇，SCI他引10000余次，H因子53。申请专利13项，授权10项。获教育部优秀科技成果奖自然科学一等奖1项，北京市科学技术奖二等奖1项和中国材料研究会科技奖一等奖1项。在国际和各类双边会议上作大会或分会邀请报告40余次。荣获北京市科技新星（2008）、教育部新世纪优秀人才（2009）、北京市优秀人才（2009）、霍英东优秀青年教师奖（2009）、青年科学之星新人奖（2010）、北京茅以升青年科技奖（2011）、绿叶生物医药杰出青年学者奖（2012）、中国化学会-英国皇家化学会青年化学奖（2013）、科技部中青年科技创新领军人才（2014）、中国电子学会优秀科技工作者（2015），全国优秀科技工作者（2016）、中国生物材料学会青年科学家奖（2018）和科睿唯安高被引科学家（2018）。正主持国家重点研发计划，国家自然科学基金委重点项目、重大项目课题等。现任Rare Metals副主编，Advanced Science (Wiley)、Scientific Reports (NPG)、Science China Materials等期刊编委，中国材料研究会常务理事、青年委员会主任委员，中国化学会理事、青年委员会主任委员，中国生物材料学会理事等。